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Identification of common features in prototype broadly neutralizing antibodies to HIV envelope V2 apex to facilitate vaccine design

Broadly neutralizing antibodies (bnAbs) directed to the V2 apex of the HIV envelope (Env) trimer isolated from individual HIV-infected donors potently neutralize diverse HIV strains, but strategies for designing immunogens to elicit bnAbs have not been identified. Here, we compared four prototypes (...

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書目詳細資料
發表在:Immunity
Main Authors: Andrabi, Raiees, Voss, James E, Liang, Chi-Hui, Briney, Bryan, McCoy, Laura E, Wu, Chung-Yi, Wong, Chi-Huey, Poignard, Pascal, Burton, Dennis R.
格式: Artigo
語言:Inglês
出版: 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4654981/
https://ncbi.nlm.nih.gov/pubmed/26588781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2015.10.014
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