Glycans function as anchors for antibodies and help drive HIV broadly neutralizing antibody development

Apex broadly neutralizing HIV antibodies (bnAbs) recognize glycans and protein surface close to the 3-fold axis of the envelope (Env) trimer and are among the most potent and broad Abs described. The evolution of apex bnAbs from one donor (CAP256) has been studied in detail and many Abs at different...

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Detalhes bibliográficos
Publicado no:Immunity
Main Authors: Andrabi, Raiees, Su, Ching-Yao, Liang, Chi-Hui, Shivatare, Sachin S., Briney, Bryan, Voss, James E., Nawazi, Salar Khan, Wu, Chung-Yi, Wong, Chi-Huey, Burton, Dennis R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5613947/
https://ncbi.nlm.nih.gov/pubmed/28916265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2017.08.006
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