Elicitation of Neutralizing Antibodies Targeting the V2 Apex of the HIV Envelope Trimer in a Wild-Type Animal Model

Recent efforts toward HIV vaccine development include the design of immunogens that can engage B cell receptors with the potential to affinity mature into broadly neutralizing antibodies (bnAbs). V2-apex bnAbs, which bind a protein-glycan region on HIV envelope glycoprotein (Env) trimer, are among t...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Voss, James E., Andrabi, Raiees, McCoy, Laura E., de Val, Natalia, Fuller, Roberta P., Messmer, Terrence, Su, Ching-Yao, Sok, Devin, Khan, Salar N., Garces, Fernando, Pritchard, Laura K., Wyatt, Richard T., Ward, Andrew B., Crispin, Max, Wilson, Ian A., Burton, Dennis R.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5640805/
https://ncbi.nlm.nih.gov/pubmed/28978475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.09.024
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