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Elicitation of Neutralizing Antibodies Targeting the V2 Apex of the HIV Envelope Trimer in a Wild-Type Animal Model
Recent efforts toward HIV vaccine development include the design of immunogens that can engage B cell receptors with the potential to affinity mature into broadly neutralizing antibodies (bnAbs). V2-apex bnAbs, which bind a protein-glycan region on HIV envelope glycoprotein (Env) trimer, are among t...
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Veröffentlicht in: | Cell Rep |
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Hauptverfasser: | , , , , , , , , , , , , , , , |
Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
Cell Press
2017
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5640805/ https://ncbi.nlm.nih.gov/pubmed/28978475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.09.024 |
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