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Identification of common features in prototype broadly neutralizing antibodies to HIV envelope V2 apex to facilitate vaccine design

Broadly neutralizing antibodies (bnAbs) directed to the V2 apex of the HIV envelope (Env) trimer isolated from individual HIV-infected donors potently neutralize diverse HIV strains, but strategies for designing immunogens to elicit bnAbs have not been identified. Here, we compared four prototypes (...

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書誌詳細
出版年:Immunity
主要な著者: Andrabi, Raiees, Voss, James E, Liang, Chi-Hui, Briney, Bryan, McCoy, Laura E, Wu, Chung-Yi, Wong, Chi-Huey, Poignard, Pascal, Burton, Dennis R.
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4654981/
https://ncbi.nlm.nih.gov/pubmed/26588781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2015.10.014
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