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Identification of common features in prototype broadly neutralizing antibodies to HIV envelope V2 apex to facilitate vaccine design

Broadly neutralizing antibodies (bnAbs) directed to the V2 apex of the HIV envelope (Env) trimer isolated from individual HIV-infected donors potently neutralize diverse HIV strains, but strategies for designing immunogens to elicit bnAbs have not been identified. Here, we compared four prototypes (...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Immunity
Main Authors: Andrabi, Raiees, Voss, James E, Liang, Chi-Hui, Briney, Bryan, McCoy, Laura E, Wu, Chung-Yi, Wong, Chi-Huey, Poignard, Pascal, Burton, Dennis R.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2015
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4654981/
https://ncbi.nlm.nih.gov/pubmed/26588781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2015.10.014
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