Benzoxaborole Antimalarial Agents. Part 4. Discovery of Potent 6-(2-(Alkoxycarbonyl)pyrazinyl-5-oxy)-1,3-dihydro-1-hydroxy-2,1-benzoxaboroles

Por Zhang, Yong-Kang, Plattner, Jacob J., Easom, Eric E., Jacobs, Robert T., Guo, Denghui, Sanders, Virginia, Freund, Yvonne R., Campo, Brice, Rosenthal, Philip J., Bu, Wei, Gamo, Francisco-Javier, Sanz, Laura M., Ge, Min, Li, Liang, Ding, Jie, Yang, Yin
Publicado no J Med Chem (2015)

Antitumor Agents 280. Multidrug Resistance-Selective Desmosdumotin B Analogues

Por Nakagawa-Goto, Kyoko, Chang, Po-Cheng, Lai, Chin-Yu, Hung, Hsin-Yi, Chen, Tzu-Hsuan, Wu, Pei-Chi, Zhu, Hao, Sedykh, Alexander, Bastow, Kenneth F., Lee, Kuo-Hsiung
Publicado em 2010

Antitumor Agents 270. Novel Substituted 6-Phenyl-4H-furo[3,2-c]pyran-4-one Derivatives as Potent and Highly Selective Anti-Breast Cancer Agents

Por Dong, Yizhou, Shi, Qian, Nakagawa-Goto, Kyoko, Wu, Pei-Chi, Morris-Natschke, Susan L., Brossi, Arnold, Bastow, Kenneth F., Lang, Jing-Yu, Hung, Mien-Chie, Lee, Kuo-Hsiung
Publicado em 2009

Anti-AIDS Agents 82: Synthesis of Seco-(3′R,4′R)-3′,4′-di-O-(S)-camphanoyl-(+)-cis-khellactone (DCK) Derivatives as Novel Anti-HIV Agents

Por Tang, Jian, Qian, Keduo, Zhang, Bei-Na, Chen, Ying, Xia, Peng, Yu, Donglei, Xia, Yi, Yang, Zheng-Yu, Chen, Chin-Ho, Morris-Natschke, Susan L., Lee, Kuo-Hsiung
Publicado em 2010

Synthesis, Biological Evaluation, and Physicochemical Property Assessment of 4-Substituted 2-phenylaminoquinazolines as Mer Tyrosine Kinase Inhibitors

Por Wang, Sheng-Biao, Cui, Mutian, Wang, Xiao-Feng, Ohkoshi, Emika, Goto, Masuo, Yang, De-Xuan, Li, Linna, Yuan, Shoujun, Morris-Natschke, Susan L., Lee, Kuo-Hsiung, Xie, Lan
Publicado no Bioorg Med Chem (2016)

Development of sigma-1 (σ(1)) receptor fluorescent ligands as versatile tools to study σ(1) receptors(✩)

Por Abate, Carmen, Riganti, Chiara, Pati, Maria Laura, Ghigo, Dario, Berardi, Francesco, Mavlyutov, Timur, Guo, Lian-Wang, Ruoho, Arnold
Publicado no Eur J Med Chem (2015)

Extended N(6) Substitution of Rigid C2-Arylethynyl Nucleosides for Exploring the Role of Extracellular Loops in Ligand Recognition at the A(3) Adenosine Receptor

Por Tosh, Dilip K., Paoletta, Silvia, Chen, Zhoumou, Moss, Steven M., Gao, Zhan-Guo, Salvemini, Daniela, Jacobson, Kenneth A.
Publicado em 2014

Design of (N)-Methanocarba Adenosine 5′-Uronamides as Species-Independent A(3) Receptor-Selective Agonists

Por Melman, Artem, Gao, Zhan-Guo, Kumar, Deepmala, Wan, Tina C., Gizewski, Elizabeth, Auchampach, John A., Jacobson, Kenneth A.
Publicado em 2008

Synthesis and Evaluation of Folate-Conjugated Phenanthraquinones for Tumor-Targeted Oxidative Chemotherapy

Por Kumar, Ajay, Chelvam, Venkatesh, Sakkarapalayam, Mahalingam, Li, Guo, Sanchez-Cruz, Pedro, Piñero, Natasha S., Low, Philip S., Alegria, Antonio E.
Publicado no Open J Med Chem (2016)

2-Dialkynyl Derivatives of (N)-Methanocarba Nucleosides: “Clickable” A(3) Adenosine Receptor-Selective Agonists

Por Tosh, Dilip K., Chinn, Moshe, Yoo, Lena S., Kang, Dong Wook, Luecke, Hans, Gao, Zhan-Guo, Jacobson, Kenneth A.
Publicado em 2009

Quantitative LC-MS/MS analysis of seven ginsenosides and three aconitum alkaloids in Shen-Fu decoction

Por Guo, Na, Liu, Mingtao, Yang, Dawei, Huang, Ying, Niu, Xiaohong, Wu, Ruifan, Liu, Ying, Ma, Guizhi, Dou, Deqiang
Publicado em 2013

Design and synthesis of novel spin-labeled camptothecin derivatives as potent cytotoxic agents

Por Zhao, Xiao-Bo, Wu, Dan, Wang, Mei-Juan, Goto, Masuo, Morris-Natschke, Susan L., Liu, Ying-Qian, Wu, Xiao-Bing, Song, Zi-Long, Zhu, Gao-Xiang, Lee, Kuo-Hsiung
Publicado no Bioorg Med Chem (2014)

Novel HIV-1 Non-nucleoside Reverse Transcriptase Inhibitor Agents: Optimization of Diarylanilines with High Potency against Wild-Type and Rilpivirine-Resistant E138K Mutant Virus

Por Liu, Na, Wei, Lei, Huang, Li, Yu, Fei, Zheng, Weifan, Qin, Bingjie, Zhu, Dong-Qin, Morris-Natschke, Susan L., Jiang, Shibo, Chen, Chin-Ho, Lee, Kuo-Hsiung, Xie, Lan
Publicado no J Med Chem (2016)

Targeting the entrance channel of NNIBP: Discovery of diarylnicotinamide 1,4-disubstituted 1,2,3-triazoles as novel HIV-1 NNRTIs with high potency against wild-type and E138K mutan...

Por Tian, Ye, Liu, Zhaoqiang, Liu, Jinghan, Huang, Boshi, Kang, Dongwei, Zhang, Heng, De Clercq, Erik, Daelemans, Dirk, Pannecouque, Christophe, Lee, Kuo-Hsiung, Chen, Chin-Ho, Zhan, Peng, Liu, Xinyong
Publicado no Eur J Med Chem (2018)

Improved synthesis of 17β-hydroxy-16α-iodo-wortmannin, 17β-hydroxy-16α-iodoPX866, and the [(131)I] analogue as useful PET tracers for PI3-kinase

Por Sun, Duoli, Bhanu Prasad, Basvoju A., Schuber, Paul T., Peng, Zhenghong, Maxwell, David S., Martin, Diana V., Guo, Liwei, Han, Dongmei, Kurihara, Hiroaki, Yang, David J., Gelovani, Juri G., Powis, Garth, Bornmann, William G.
Publicado em 2013

Erythrofordins D and E, two new cassaine-type diterpenes from Erythrophleum suaveolens

Por Grkovic, Tanja, Evans, Jason R., Akee, Rhone K., Guo, Liang, Davis, Myrtle, Jato, Johnson, Grothaus, Paul G., Ahalt-Gottholm, Michelle, Hollingshead, Melinda, Collins, Jerry M., Newman, David J., O’Keefe, Barry R.
Publicado no Bioorg Med Chem Lett (2018)

Synthesis, Molecular Modeling, and Biological Evaluation of Novel RAD51 Inhibitors

Por Zhu, Jiewen, Chen, Hongyuan, Guo, Xuning Emily, Qiu, Xiao-Long, Hu, Chun-Mei, Chamberlin, A. Richard, Lee, Wen-Hwa
Publicado no Eur J Med Chem (2015)

Small Molecule Inhibits Activity of Scavenger Receptor A: Lead Identification and Preliminary Studies

Por Yuan, Yunyun, Li, Xia, Zaidi, Saheem A., Arnatt, Christopher K., Yu, Xiaofei, Guo, Chunqing, Wang, Xiang-Yang, Zhang, Yan
Publicado no Bioorg Med Chem Lett (2015)

Design, synthesis, and discovery of 5-((1,3-diphenyl-1H-pyrazol-4-yl)methylene)pyrimidine-2,4,6(1H,3H,5H)-triones and related derivatives as novel inhibitors of mPGES-1

Por Ding, Kai, Zhou, Ziyuan, Zhou, Shuo, Yuan, Yaxia, Kim, Kyungbo, Zhang, Ting, Zheng, Xirong, Zheng, Fang, Zhan, Chang-Guo
Publicado no Bioorg Med Chem Lett (2018)

2-Triazole-Substituted Adenosines: A New Class of Selective A(3) Adenosine Receptor Agonists, Partial Agonists, and Antagonists

Por Cosyn, Liesbet, Palaniappan, Krishnan K., Kim, Soo-Kyung, Duong, Heng T., Gao, Zhan-Guo, Jacobson, Kenneth A., Van Calenbergh, Serge
Publicado no J Med Chem (2006)