Φορτώνει......
Extended N(6) Substitution of Rigid C2-Arylethynyl Nucleosides for Exploring the Role of Extracellular Loops in Ligand Recognition at the A(3) Adenosine Receptor
2-Arylethynyl-(N)-methanocarba adenosine 5′-methyluronamides containing rigid N(6)-(trans-2-phenylcyclopropyl) and 2-phenylethynyl groups were synthesized as agonists for probing structural features of the A(3) adenosine receptor (AR). Radioligand binding confirmed A(3)AR selectivity and N(6)-1S,2R...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2014
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4158450/ https://ncbi.nlm.nih.gov/pubmed/24969016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2014.06.006 |
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