Rational Design of Sulfonated A(3) Adenosine Receptor-Selective Nucleosides as Pharmacological Tools to Study Chronic Neuropathic Pain

(N)-Methanocarba (bicyclo[3.1.0]hexane)-adenosine derivatives were probed for sites of charged sulfonate substitution, which precludes diffusion across biological membranes, e.g. blood brain barrier. Molecular modeling predicted that sulfonate groups on C2-phenylethynyl substituents would provide hi...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Paoletta, Silvia, Tosh, Dilip K., Finley, Amanda, Gizewski, Elizabeth T., Moss, Steven M., Gao, Zhan-Guo, Auchampach, John A., Salvemini, Daniela, Jacobson, Kenneth A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3858399/
https://ncbi.nlm.nih.gov/pubmed/23789857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm4007966
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia