Two Distinct Phosphorylation Pathways Have Additive Effects on Abl Family Kinase Activation

by Tanis, Keith Q., Veach, Darren, Duewel, Henry S., Bornmann, William G., Koleske, Anthony J.
Published 2003

Asymmetric Synthesis of the C1-C6 Portion of the Psymberin Using an Evans Chiral Auxiliary

by Pal, Ashutosh, Peng, Zhenghong, Schuber, Paul T., Bhanu Prasad, Basvoju A., Bornmann, William G.
Published 2013

DEMONSTRATION OF MICROTUBULE-LIKE STRUCTURES FORMED WITH (−)-RHAZINILAM FROM PURIFIED TUBULIN OUTSIDE OF CELLS AND A SIMPLE TUBULIN-BASED ASSAY FOR EVALUATION OF ANALOG ACTIVITY

by Edler, Michael C., Yang, Guangli, Jung, M. Katherine, Bai, Ruoli, Bornmann, William G., Hamel, Ernest
Published 2009

Synthesis of a Macrocycle Based on Linked Amino Acid Mimetics (LAAM)

by Maxwell, David S., Sun, Duoli, Peng, Zhenghong, Martin, Diana V., Bhanu Prasad, Basvoju A., Bornmann, William G.
Published 2013

The anti-angiogenic agent fumagillin covalently binds and inhibits the methionine aminopeptidase, MetAP-2

by Sin, Ny, Meng, Lihao, Wang, Margaret Q. W., Wen, James J., Bornmann, William G., Crews, Craig M.
Published 1997

PD166326, a novel tyrosine kinase inhibitor, has greater antileukemic activity than imatinib mesylate in a murine model of chronic myeloid leukemia

by Wolff, Nicholas C., Veach, Darren R., Tong, William P., Bornmann, William G., Clarkson, Bayard, Ilaria, Robert L.
Published 2005

A Practical Synthesis and X-ray Crystallographic Analysis of Dithymoquinone, a Photodimer of Thymoquinone

by Myers, Alan L., Zhang, Yan-Ping, Kramer, Mark A., Bornmann, William G., Kaseb, Ahmed, Yang, Peiying, Tran, Hai T.
Published 2012

Curcumin Glucuronides: Assessing the Proliferative Activity against Human Cell Lines

by Pal, Ashutosh, Sung, Bokyung, Prasad, Basvoju A. Bhanu, Schuber, Paul T., Prasad, Sahdeo, Aggarwal, Bharat B., Bornmann, William G.
Published 2013

Indole-3-carbinol and its N-alkoxy derivatives preferentially target ERα-positive breast cancer cells

by Caruso, Joseph A, Campana, Rody, Wei, Caimiao, Su, Chun-Hui, Hanks, Amanda M, Bornmann, William G, Keyomarsi, Khandan
Published in Cell Cycle (2014)

Activity of lapatinib is independent of EGFR expression level in HER2-overexpressing breast cancer cells

by Zhang, Dongwei, Pal, Ashutosh, Bornmann, William G., Yamasaki, Fumiyuki, Esteva, Francisco J., Hortobagyi, Gabriel N., Bartholomeusz, Chandra, Ueno, Naoto T.
Published 2008

Role of c-Abl Kinase in DNA Mismatch Repair-dependent G(2) Cell Cycle Checkpoint Arrest Responses

by Wagner, Mark W., Li, Long Shan, Morales, Julio C., Galindo, Cristi L., Garner, Harold R., Bornmann, William G., Boothman, David A.
Published 2008

STAT3 mediates resistance to MEK inhibitor through microRNA miR-17

by Dai, Bingbing, Meng, Jieru, Peyton, Michael, Girard, Luc, Bornmann, William G., Ji, Lin, Minna, John D., Fang, Bingliang, Roth, Jack A.
Published 2011

Gleevec inhibits β-amyloid production but not Notch cleavage

by Netzer, William J., Dou, Fei, Cai, Dongming, Veach, Darren, Jean, Stephanie, Li, Yueming, Bornmann, William G., Clarkson, Bayard, Xu, Huaxi, Greengard, Paul
Published 2003

Intratumoral Delivery of β-Lapachone via Polymer Implants for Prostate Cancer Therapy

by Dong, Ying, Chin, Shook-Fong, Blanco, Elvin, Bey, Erik A, Kabbani, Wareef, Xie, Xian-Jin, Bornmann, William G., Boothman, David A., Gao, Jinming
Published 2009

Design and Synthesis of an Inositol Phosphate Analog Based on Computational Docking Studies

by Peng, Zhenghong, Maxwell, David, Sun, Duoli, Ying, Yunming, Schuber, Paul T., Bhanu Prasad, Basvoju A., Gelovani, Juri, Yung, Wai-Kwan Alfred, Bornmann, William G.
Published 2013

An NQO1- and PARP-1-mediated cell death pathway induced in non-small-cell lung cancer cells by β-lapachone

by Bey, Erik A., Bentle, Melissa S., Reinicke, Kathryn E., Dong, Ying, Yang, Chin-Rang, Girard, Luc, Minna, John D., Bornmann, William G., Gao, Jinming, Boothman, David A.
Published 2007

Association Between Imatinib-Resistant BCR-ABL Mutation-Negative Leukemia and Persistent Activation of LYN Kinase

by Wu, Ji, Meng, Feng, Kong, Ling-Yuan, Peng, Zhenghong, Ying, Yunming, Bornmann, William G., Darnay, Bryant G., Lamothe, Betty, Sun, Hanshi, Talpaz, Moshe, Donato, Nicholas J.
Published 2008

Decitabine and suberoylanilide hydroxamic acid (SAHA) inhibit growth of ovarian cancer cell lines and xenografts while inducing expression of imprinted tumor suppressor genes, apop...

by Chen, Min-Yu, Liao, Warren S.-L., Lu, Zhen, Bornmann, William G., Hennessey, Violeta, Washington, Michele N., Rosner, Gary L., Yu, Yinhua, Ahmed, Ahmed Ashour, Bast, Robert C.
Published 2011

Mechanism of Activation and Inhibition of the HER4/ErbB4 Kinase

by Qiu, Chen, Tarrant, Mary K., Choi, Sung Hee, Sathyamurthy, Aruna, Bose, Ron, Banjade, Sudeep, Pal, Ashutosh, Bornmann, William G., Lemmon, Mark A., Cole, Philip A., Leahy, Daniel J.
Published 2008

Combination Treatment with MEK and AKT Inhibitors Is More Effective than Each Drug Alone in Human Non-Small Cell Lung Cancer In Vitro and In Vivo

by Meng, Jieru, Dai, Bingbing, Fang, Bingliang, Bekele, B. Nebiyou, Bornmann, William G., Sun, Duoli, Peng, Zhenghong, Herbst, Roy S., Papadimitrakopoulou, Vassiliki, Minna, John D., Peyton, Michael, Roth, Jack A.
Published 2010