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Indole-3-carbinol and its N-alkoxy derivatives preferentially target ERα-positive breast cancer cells

Indole-3-carbinol (I3C) is a natural anti-carcinogenic compound found at high concentrations in Brassica vegetables. I3C was recently reported to inhibit neutrophil elastase (NE) activity, while consequently limiting the proteolytic processing of full length cyclin E into pro-tumorigenic low molecul...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Caruso, Joseph A, Campana, Rody, Wei, Caimiao, Su, Chun-Hui, Hanks, Amanda M, Bornmann, William G, Keyomarsi, Khandan
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614451/
https://ncbi.nlm.nih.gov/pubmed/25486199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2015.942210
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