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Combined Luteolin and Indole-3-Carbinol Synergistically Constrains ERα-Positive Breast Cancer by Dual Inhibiting Estrogen Receptor Alpha and Cyclin-Dependent Kinase 4/6 Pathway in Cultured Cells and Xenograft Mice

SIMPLE SUMMARY: Anti-cancer effects of bioactive compounds have been extensively investigated; however, the effective dosages of the bioactive compounds are too high to be obtained by oral intake. Our study aimed to assess if combined two bioactive compounds, luteolin (LUT) and indole-3-carbinol (I3...

詳細記述

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書誌詳細
出版年:Cancers (Basel)
主要な著者: Wang, Xiaoyong, Zhang, Lijuan, Dai, Qi, Si, Hongzong, Zhang, Longyun, Eltom, Sakina E., Si, Hongwei
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8123907/
https://ncbi.nlm.nih.gov/pubmed/33925607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13092116
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