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Combined Luteolin and Indole-3-Carbinol Synergistically Constrains ERα-Positive Breast Cancer by Dual Inhibiting Estrogen Receptor Alpha and Cyclin-Dependent Kinase 4/6 Pathway in Cultured Cells and Xenograft Mice

SIMPLE SUMMARY: Anti-cancer effects of bioactive compounds have been extensively investigated; however, the effective dosages of the bioactive compounds are too high to be obtained by oral intake. Our study aimed to assess if combined two bioactive compounds, luteolin (LUT) and indole-3-carbinol (I3...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cancers (Basel)
Main Authors: Wang, Xiaoyong, Zhang, Lijuan, Dai, Qi, Si, Hongzong, Zhang, Longyun, Eltom, Sakina E., Si, Hongwei
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8123907/
https://ncbi.nlm.nih.gov/pubmed/33925607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13092116
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