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PD166326, a novel tyrosine kinase inhibitor, has greater antileukemic activity than imatinib mesylate in a murine model of chronic myeloid leukemia

Imatinib mesylate is highly effective in newly diagnosed chronic myeloid leukemia (CML), but BCR/ABL (breakpoint cluster region/abelson murine leukemia)–positive progenitors persist in most patients with CML treated with imatinib mesylate, indicating the need for novel therapeutic approaches. In thi...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Wolff, Nicholas C., Veach, Darren R., Tong, William P., Bornmann, William G., Clarkson, Bayard, Ilaria, Robert L.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: © 2005 by The American Society of Hematology 2005
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895078/
https://ncbi.nlm.nih.gov/pubmed/15657179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-09-3534
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