Selective tyrosine kinase inhibition by imatinib mesylate for the treatment of autoimmune arthritis

Tyrosine kinases play a central role in the activation of signal transduction pathways and cellular responses that mediate the pathogenesis of rheumatoid arthritis. Imatinib mesylate (imatinib) is a tyrosine kinase inhibitor developed to treat Bcr/Abl-expressing leukemias and subsequently found to t...

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Detalhes bibliográficos
Main Authors: Paniagua, Ricardo T., Sharpe, Orr, Ho, Peggy P., Chan, Steven M., Chang, Anna, Higgins, John P., Tomooka, Beren H., Thomas, Fiona M., Song, Jason J., Goodman, Stuart B., Lee, David M., Genovese, Mark C., Utz, Paul J., Steinman, Lawrence, Robinson, William H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564430/
https://ncbi.nlm.nih.gov/pubmed/16981009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI28546
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