Epitope spreading to citrullinated antigens in mouse models of autoimmune arthritis and demyelination

INTRODUCTION: Anti-citrullinated protein antibodies have a diagnostic role in rheumatoid arthritis (RA); however, little is known about their origins and contribution to pathogenesis. Citrullination is the post-translational conversion of arginine to citrulline by peptidyl arginine deiminase, and in...

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Bibliografiske detaljer
Main Authors: Kidd, Brian A, Ho, Peggy P, Sharpe, Orr, Zhao, Xiaoyan, Tomooka, Beren H, Kanter, Jennifer L, Steinman, Lawrence, Robinson, William H
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2008
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2592807/
https://ncbi.nlm.nih.gov/pubmed/18826638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2523
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