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Epitope spreading to citrullinated antigens in mouse models of autoimmune arthritis and demyelination
INTRODUCTION: Anti-citrullinated protein antibodies have a diagnostic role in rheumatoid arthritis (RA); however, little is known about their origins and contribution to pathogenesis. Citrullination is the post-translational conversion of arginine to citrulline by peptidyl arginine deiminase, and in...
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| Main Authors: | , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
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BioMed Central
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2592807/ https://ncbi.nlm.nih.gov/pubmed/18826638 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2523 |
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