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Intratumoral Delivery of β-Lapachone via Polymer Implants for Prostate Cancer Therapy
PURPOSE: β-Lapachone (β-lap, ARQ 501) is a novel anticancer agent with selectivity against prostate cancer cells over-expressing the NAD(P)H:quinone oxidoreductase-1 (NQO1) enzyme. Lack of solubility and an efficient drug delivery strategy limits this compound in clinical applications. In this study...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2845536/ https://ncbi.nlm.nih.gov/pubmed/19118040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-1691 |
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