Intratumoral Delivery of β-Lapachone via Polymer Implants for Prostate Cancer Therapy

PURPOSE: β-Lapachone (β-lap, ARQ 501) is a novel anticancer agent with selectivity against prostate cancer cells over-expressing the NAD(P)H:quinone oxidoreductase-1 (NQO1) enzyme. Lack of solubility and an efficient drug delivery strategy limits this compound in clinical applications. In this study...

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Detaylı Bibliyografya
Asıl Yazarlar: Dong, Ying, Chin, Shook-Fong, Blanco, Elvin, Bey, Erik A, Kabbani, Wareef, Xie, Xian-Jin, Bornmann, William G., Boothman, David A., Gao, Jinming
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845536/
https://ncbi.nlm.nih.gov/pubmed/19118040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-1691
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