β-Lapachone Micellar Nanotherapeutics for Non-Small Cell Lung Cancer Therapy

Lung cancer is the leading cause of cancer-related deaths with current chemotherapies lacking adequate specificity and efficacy. β-Lapachone (β-lap) is a novel anticancer drug that is bioactivated by NAD(P)H:quinone oxidoreductase-1 (NQO1), an enzyme found specifically overexpressed in non-small cel...

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Detalhes bibliográficos
Main Authors: Blanco, Elvin, Bey, Erik A., Khemtong, Chalermchai, Yang, Su-Geun, Setti-Guthi, Jagadeesh, Chen, Huabing, Kessinger, Chase W., Carnevale, Kevin A., Bornmann, William G., Boothman, David A., Gao, Jinming
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873165/
https://ncbi.nlm.nih.gov/pubmed/20460521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-3995
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