Gleevec inhibits β-amyloid production but not Notch cleavage

Eitemau Tebyg

• Gleevec shifts APP processing from a β-cleavage to a nonamyloidogenic cleavage
  gan: Netzer, William J., et al.
  Cyhoeddwyd: (2017)
• Presenilin-1 uses phospholipase D1 as a negative regulator of β-amyloid formation
  gan: Cai, Dongming, et al.
  Cyhoeddwyd: (2006)
• Gleevec Increases Levels of the Amyloid Precursor Protein Intracellular Domain and of the Amyloid-β–degrading Enzyme Neprilysin
  gan: Eisele, Yvonne S., et al.
  Cyhoeddwyd: (2007)
• Regulation of β cleavage of amyloid precursor protein
  gan: Wang, Jun-Feng, et al.
  Cyhoeddwyd: (2010)
• An antibody to the β-secretase cleavage site on amyloid β-protein precursor inhibits amyloid β production
  gan: Thomas, Rhian S., et al.
  Cyhoeddwyd: (2006)