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An antibody to the β-secretase cleavage site on amyloid β-protein precursor inhibits amyloid β production
Proteolytic cleavage of amyloid β-protein precursor (AβPP) by β– and γ–secretases results in production of the amyloid β peptide (Aβ) that accumulates in the brains of sufferers of Alzheimer’s Disease (AD). We have developed a monoclonal antibody, 2B12, which binds in the vicinity of the β-secretase...
Tallennettuna:
| Julkaisussa: | J Alzheimers Dis |
|---|---|
| Päätekijät: | , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2006
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4492742/ https://ncbi.nlm.nih.gov/pubmed/17183149 |
| Tagit: |
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