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Inhibition of amyloid precursor protein processing by β-secretase through site-directed antibodies
Amyloid-β peptide (AβP) that accumulates in the Alzheimer's diseased brain is derived from proteolytic processing of the amyloid precursor protein (APP) by means of β- and γ-secretases. The β-secretase APP cleaving enzyme (BACE), which generates the N terminus of AβP, has become a target of int...
में बचाया:
| मुख्य लेखकों: | , , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
National Academy of Sciences
2005
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1140443/ https://ncbi.nlm.nih.gov/pubmed/15894613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502427102 |
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