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Divalent cation tolerance protein binds to β-secretase and inhibits the processing of amyloid precursor protein☆
The deposition of amyloid-beta is a pathological hallmark of Alzheimer's disease. Amyloid-beta is derived from amyloid precursor protein through sequential proteolytic cleavages by β-secretase (beta-site amyloid precursor protein-cleaving enzyme 1) and γ-secretase. To further elucidate the role...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Medknow Publications & Media Pvt Ltd
2013
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4145881/ https://ncbi.nlm.nih.gov/pubmed/25206392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3969/j.issn.1673-5374.2013.11.004 |
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