लोड हो रहा है...
β-Amyloid Precursor Protein Mutants Respond to γ-Secretase Modulators
Pathogenic generation of the 42-amino acid variant of the amyloid β-peptide (Aβ) by β- and γ-secretase cleavage of the β-amyloid precursor protein (APP) is believed to be causative for Alzheimer disease (AD). Lowering of Aβ(42) production by γ-secretase modulators (GSMs) is a hopeful approach toward...
में बचाया:
| मुख्य लेखकों: | , , , , , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
American Society for Biochemistry and Molecular Biology
2010
|
| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2878544/ https://ncbi.nlm.nih.gov/pubmed/20348104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.103283 |
| टैग : |
टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!
|