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Inhibition of amyloid-β production by anti-amyloid precursor protein antibodies in primary mouse cortical neurones
Current therapies for Alzheimer’s disease (AD) only treat the symptoms of the disease. We have previously developed a novel monoclonal antibody, 2B3, which binds to the β-secretase cleavage site in amyloid precursor protein (APP) and reduces the production of amyloid-β (Aβ) in human cell lines. To d...
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| Publicado no: | Neuroreport |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4493351/ https://ncbi.nlm.nih.gov/pubmed/24145776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WNR.0000000000000055 |
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