PAT1 inversely regulates the surface Amyloid Precursor Protein level in mouse primary neurons

BACKGROUND: The amyloid precursor protein (APP) is a key molecule in Alzheimer disease. Its localization at the cell surface can trigger downstream signaling and APP cleavages. APP trafficking to the cell surface in neurons is not clearly understood and may be related to the interactions with its pa...

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Vydáno v:BMC Neurosci
Hlavní autoři: Dilsizoglu Senol, Aysegul, Tagliafierro, Lidia, Huguet, Léa, Gorisse-Hussonnois, Lucie, Chasseigneaux, Stéphanie, Allinquant, Bernadette
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355975/
https://ncbi.nlm.nih.gov/pubmed/25880931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-015-0152-8
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