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PAT1 inversely regulates the surface Amyloid Precursor Protein level in mouse primary neurons
BACKGROUND: The amyloid precursor protein (APP) is a key molecule in Alzheimer disease. Its localization at the cell surface can trigger downstream signaling and APP cleavages. APP trafficking to the cell surface in neurons is not clearly understood and may be related to the interactions with its pa...
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| 出版年: | BMC Neurosci |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2015
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4355975/ https://ncbi.nlm.nih.gov/pubmed/25880931 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-015-0152-8 |
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