PAT1 inversely regulates the surface Amyloid Precursor Protein level in mouse primary neurons

BACKGROUND: The amyloid precursor protein (APP) is a key molecule in Alzheimer disease. Its localization at the cell surface can trigger downstream signaling and APP cleavages. APP trafficking to the cell surface in neurons is not clearly understood and may be related to the interactions with its pa...

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Detalhes bibliográficos
Publicado no:BMC Neurosci
Main Authors: Dilsizoglu Senol, Aysegul, Tagliafierro, Lidia, Huguet, Léa, Gorisse-Hussonnois, Lucie, Chasseigneaux, Stéphanie, Allinquant, Bernadette
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355975/
https://ncbi.nlm.nih.gov/pubmed/25880931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-015-0152-8
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