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PAT1 inversely regulates the surface Amyloid Precursor Protein level in mouse primary neurons
BACKGROUND: The amyloid precursor protein (APP) is a key molecule in Alzheimer disease. Its localization at the cell surface can trigger downstream signaling and APP cleavages. APP trafficking to the cell surface in neurons is not clearly understood and may be related to the interactions with its pa...
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| Publicado no: | BMC Neurosci |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4355975/ https://ncbi.nlm.nih.gov/pubmed/25880931 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-015-0152-8 |
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