Carregant...

Cytoplasmic SET induces tau hyperphosphorylation through a decrease of methylated phosphatase 2A

BACKGROUND: The neuronal cytoplasmic localization of SET, an inhibitor of the phosphatase 2A (PP2A), results in tau hyperphosphorylation in the brains of Alzheimer patients through mechanisms that are still not well defined. RESULTS: We used primary neurons and mouse brain slices to show that SET is...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Chasseigneaux, Stéphanie, Clamagirand, Christine, Huguet, Léa, Gorisse-Hussonnois, Lucie, Rose, Christiane, Allinquant, Bernadette
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4086270/
https://ncbi.nlm.nih.gov/pubmed/24981783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-15-82
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!