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Activation of Protein Phosphatase 2B and Hyperphosphorylation of Tau in Alzheimer's Disease

Protein phosphatase 2B (PP2B) is one of the major brain phosphatases and can dephosphorylate tau at several phosphorylation sites in vitro. Previous studies that measured PP2B activity in human brain crude extracts showed that PP2B activity was either unchanged or decreased in AD brain. These result...

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Bibliografski detalji
Glavni autori: Qian, Wei, Yin, Xiaomin, Hu, Wen, Shi, Jianhua, Gu, Jianlan, Grundke-Iqbal, Inge, Iqbal, Khalid, Gong, Cheng-Xin, Liu, Fei
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377165/
https://ncbi.nlm.nih.gov/pubmed/21157033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2010-100987
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