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Activation of Protein Phosphatase 2B and Hyperphosphorylation of Tau in Alzheimer's Disease

Protein phosphatase 2B (PP2B) is one of the major brain phosphatases and can dephosphorylate tau at several phosphorylation sites in vitro. Previous studies that measured PP2B activity in human brain crude extracts showed that PP2B activity was either unchanged or decreased in AD brain. These result...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Qian, Wei, Yin, Xiaomin, Hu, Wen, Shi, Jianhua, Gu, Jianlan, Grundke-Iqbal, Inge, Iqbal, Khalid, Gong, Cheng-Xin, Liu, Fei
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377165/
https://ncbi.nlm.nih.gov/pubmed/21157033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2010-100987
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