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Activation of Protein Phosphatase 2B and Hyperphosphorylation of Tau in Alzheimer's Disease
Protein phosphatase 2B (PP2B) is one of the major brain phosphatases and can dephosphorylate tau at several phosphorylation sites in vitro. Previous studies that measured PP2B activity in human brain crude extracts showed that PP2B activity was either unchanged or decreased in AD brain. These result...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3377165/ https://ncbi.nlm.nih.gov/pubmed/21157033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2010-100987 |
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