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Reduced O-GlcNAcylation links lower brain glucose metabolism and tau pathology in Alzheimer's disease

It has been established for a long time that brain glucose metabolism is impaired in Alzheimer's disease. Recent studies have demonstrated that impaired brain glucose metabolism precedes the appearance of clinical symptoms, implying its active role in the development of Alzheimer's disease...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Liu, Fei, Shi, Jianhua, Tanimukai, Hitoshi, Gu, Jinhua, Gu, Jianlan, Grundke-Iqbal, Inge, Iqbal, Khalid, Gong, Cheng-Xin
פורמט: Artigo
שפה:Inglês
יצא לאור: Oxford University Press 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2702834/
https://ncbi.nlm.nih.gov/pubmed/19451179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awp099
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