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Reduced O-GlcNAcylation links lower brain glucose metabolism and tau pathology in Alzheimer's disease

It has been established for a long time that brain glucose metabolism is impaired in Alzheimer's disease. Recent studies have demonstrated that impaired brain glucose metabolism precedes the appearance of clinical symptoms, implying its active role in the development of Alzheimer's disease...

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Detalhes bibliográficos
Main Authors: Liu, Fei, Shi, Jianhua, Tanimukai, Hitoshi, Gu, Jinhua, Gu, Jianlan, Grundke-Iqbal, Inge, Iqbal, Khalid, Gong, Cheng-Xin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2702834/
https://ncbi.nlm.nih.gov/pubmed/19451179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awp099
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