Reduced O-GlcNAcylation links lower brain glucose metabolism and tau pathology in Alzheimer's disease

It has been established for a long time that brain glucose metabolism is impaired in Alzheimer's disease. Recent studies have demonstrated that impaired brain glucose metabolism precedes the appearance of clinical symptoms, implying its active role in the development of Alzheimer's disease...

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Bibliographic Details
Main Authors: Liu, Fei, Shi, Jianhua, Tanimukai, Hitoshi, Gu, Jinhua, Gu, Jianlan, Grundke-Iqbal, Inge, Iqbal, Khalid, Gong, Cheng-Xin
Format: Artigo
Language:Inglês
Published: Oxford University Press 2009
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2702834/
https://ncbi.nlm.nih.gov/pubmed/19451179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awp099
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