Reduced O-GlcNAcylation links lower brain glucose metabolism and tau pathology in Alzheimer's disease

It has been established for a long time that brain glucose metabolism is impaired in Alzheimer's disease. Recent studies have demonstrated that impaired brain glucose metabolism precedes the appearance of clinical symptoms, implying its active role in the development of Alzheimer's disease...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Liu, Fei, Shi, Jianhua, Tanimukai, Hitoshi, Gu, Jinhua, Gu, Jianlan, Grundke-Iqbal, Inge, Iqbal, Khalid, Gong, Cheng-Xin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2009
Schlagworte:
Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2702834/
https://ncbi.nlm.nih.gov/pubmed/19451179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awp099
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