Dysregulation of Insulin Signaling, Glucose Transporters, O-GlcNAcylation, and Phosphorylation of Tau and Neurofilaments in the Brain : Implication for Alzheimer’s Disease

Recent studies have suggested a possible role of insulin dysfunction in the pathogenesis of sporadic Alzheimer’s disease (AD). In AD, brain glucose metabolism is impaired, and this impairment appears to precede the pathology and clinical symptoms of the disease. However, the exact contribution of im...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Deng, Yanqiu, Li, Bin, Liu, Ying, Iqbal, Khalid, Grundke-Iqbal, Inge, Gong, Cheng-Xin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Investigative Pathology 2009
Gaiak:
Regular Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774072/
https://ncbi.nlm.nih.gov/pubmed/19815707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.090157
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