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Regulation between O-GlcNAcylation and phosphorylation of neurofilament-M and their dysregulation in Alzheimer disease

The medium subunit of neurofilament (NF-M) is extensively modified by phosphate and O-linked β-N-acetylglucosamine (O-GlcNAc). Phosphorylation of NF-M plays a critical role in regulating its translocation, filament formation, and function. However, the regulation of NF-M phosphorylation and the role...

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Detalhes bibliográficos
Main Authors: Deng, Yanqiu, Li, Bin, Liu, Fei, Iqbal, Khalid, Grundke-Iqbal, Inge, Brandt, Roland, Gong, Cheng-Xin
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2262915/
https://ncbi.nlm.nih.gov/pubmed/17687114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.07-8309com
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