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O-GlcNAcylation regulates phosphorylation of tau: A mechanism involved in Alzheimer's disease
Microtubule-associated protein tau is abnormally hyperphosphorylated and aggregated into neurofibrillary tangles in brains of individuals with Alzheimer's disease (AD) and other tauopathies. Tau pathology is critical to pathogenesis and correlates to the severity of dementia. However, the mecha...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC490015/ https://ncbi.nlm.nih.gov/pubmed/15249677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400348101 |
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