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O-GlcNAcylation regulates phosphorylation of tau: A mechanism involved in Alzheimer's disease
Microtubule-associated protein tau is abnormally hyperphosphorylated and aggregated into neurofibrillary tangles in brains of individuals with Alzheimer's disease (AD) and other tauopathies. Tau pathology is critical to pathogenesis and correlates to the severity of dementia. However, the mecha...
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| Asıl Yazarlar: | , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
National Academy of Sciences
2004
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC490015/ https://ncbi.nlm.nih.gov/pubmed/15249677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400348101 |
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