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O-GlcNAcylation regulates phosphorylation of tau: A mechanism involved in Alzheimer's disease

Microtubule-associated protein tau is abnormally hyperphosphorylated and aggregated into neurofibrillary tangles in brains of individuals with Alzheimer's disease (AD) and other tauopathies. Tau pathology is critical to pathogenesis and correlates to the severity of dementia. However, the mecha...

詳細記述

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書誌詳細
主要な著者: Liu, Fei, Iqbal, Khalid, Grundke-Iqbal, Inge, Hart, Gerald W., Gong, Cheng-Xin
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC490015/
https://ncbi.nlm.nih.gov/pubmed/15249677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400348101
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