Diverse Regulation of AKT and GSK-3β by O-GlcNAcylation in Various Types of Cells

Protein kinase B (AKT) and glycogen synthase kinase-3β (GSK-3β) are major components of insulin-AKT signaling that plays crucial roles in various types of tissue. Recent studies found that these two kinases are modified posttranslationally by O-GlcNAcylation. Here, we demonstrate that O-GlcNAcylatio...

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Main Authors: Shi, Jianhua, Wu, Shiliang, Dai, Chun-ling, Li, Yi, Inge-Grundke-Iqbal, Iqbal, Khalid, Liu, Fei, Gong, Cheng-Xin
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407308/
https://ncbi.nlm.nih.gov/pubmed/22687243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2012.05.063
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