Tau Biology and Tau-Directed Therapies for Alzheimer’s Disease

Por Bakota, Lidia, Brandt, Roland
Publicado no Drugs (2016)

Signaling pathways and posttranslational modifications of tau in Alzheimer's disease: the humanization of yeast cells

Por Heinisch, Jürgen J., Brandt, Roland
Publicado no Microb Cell (2016)

Real‐time three‐dimensional echocardiographic diagnosis of postmyocardial infarction ventricular septal defect and guidance of transcatheter closure

Por Brandt, Roland R, Elsaesser, Albrecht, Hamm, Christian W
Publicado em 2007

A Refined Reaction-Diffusion Model of Tau-Microtubule Dynamics and Its Application in FDAP Analysis

Por Igaev, Maxim, Janning, Dennis, Sündermann, Frederik, Niewidok, Benedikt, Brandt, Roland, Junge, Wolfgang
Publicado no Biophys J (2014)

Presence of a carboxy-terminal pseudorepeat and disease-like pseudohyperphosphorylation critically influence tau’s interaction with microtubules in axon-like processes

Por Niewidok, Benedikt, Igaev, Maxim, Sündermann, Frederik, Janning, Dennis, Bakota, Lidia, Brandt, Roland
Publicado no Mol Biol Cell (2016)

Evaluation Of Atrial Fibrillation Burden Before Catheter Ablation Predicts Outcome After Pulmonary Vein Isolation

Por Berkowitsch, Alexander, Neumann, Thomas, Kuniss, Malte, Brandt, Roland, Zaltsberg, Sergej, Pitschner, Heinz F
Publicado em 2009

Region-specific dendritic simplification induced by Aβ, mediated by tau via dysregulation of microtubule dynamics: a mechanistic distinct event from other neurodegenerative process...

Por Golovyashkina, Nataliya, Penazzi, Lorène, Ballatore, Carlo, Smith, Amos B., Bakota, Lidia, Brandt, Roland
Publicado no Mol Neurodegener (2015)

Regulation between O-GlcNAcylation and phosphorylation of neurofilament-M and their dysregulation in Alzheimer disease

Por Deng, Yanqiu, Li, Bin, Liu, Fei, Iqbal, Khalid, Grundke-Iqbal, Inge, Brandt, Roland, Gong, Cheng-Xin
Publicado em 2007

RNA Protein Granules Modulate tau Isoform Expression and Induce Neuronal Sprouting

Por Moschner, Katharina, Sündermann, Frederik, Meyer, Heiko, da Graca, Abel Pereira, Appel, Neele, Paululat, Achim, Bakota, Lidia, Brandt, Roland
Publicado em 2014

Pseudohyperphosphorylation of tau is sufficient to induce aberrant sprouting and activation of ERK1/2 in transgenic mice

Por Monyer Hannah, von Engelhardt Jacob, Götz Jürgen, Schultz Christian, Fath Thomas, Kosfeld Anne, Selle Karolin, Hundelt Monika, Brandt Roland
Publicado em 2007-03-01

The frontotemporal dementia mutation R406W blocks tau’s interaction with the membrane in an annexin A2–dependent manner

Por Gauthier-Kemper, Anne, Weissmann, Carina, Golovyashkina, Nataliya, Sebö-Lemke, Zsofia, Drewes, Gerard, Gerke, Volker, Heinisch, Jürgen J., Brandt, Roland
Publicado em 2011

Single-molecule tracking of tau reveals fast kiss-and-hop interaction with microtubules in living neurons

Por Janning, Dennis, Igaev, Maxim, Sündermann, Frederik, Brühmann, Jörg, Beutel, Oliver, Heinisch, Jürgen J., Bakota, Lidia, Piehler, Jacob, Junge, Wolfgang, Brandt, Roland
Publicado no Mol Biol Cell (2014)

Aβ-mediated spine changes in the hippocampus are microtubule-dependent and can be reversed by a subnanomolar concentration of the microtubule-stabilizing agent epothilone D

Por Penazzi, Lorène, Tackenberg, Christian, Ghori, Adnan, Golovyashkina, Nataliya, Niewidok, Benedikt, Selle, Karolin, Ballatore, Carlo, Smith, Amos B., Bakota, Lidia, Brandt, Roland
Publicado no Neuropharmacology (2016)

Interplay between phosphorylation and palmitoylation mediates plasma membrane targeting and sorting of GAP43

Por Gauthier-Kemper, Anne, Igaev, Maxim, Sündermann, Frederik, Janning, Dennis, Brühmann, Jörg, Moschner, Katharina, Reyher, Hans-Jürgen, Junge, Wolfgang, Glebov, Konstantin, Walter, Jochen, Bakota, Lidia, Brandt, Roland
Publicado em 2014

Human High Temperature Requirement Serine Protease A1 (HTRA1) Degrades Tau Protein Aggregates

Por Tennstaedt, Annette, Pöpsel, Simon, Truebestein, Linda, Hauske, Patrick, Brockmann, Anke, Schmidt, Nina, Irle, Inga, Sacca, Barbara, Niemeyer, Christof M., Brandt, Roland, Ksiezak-Reding, Hanna, Tirniceriu, Anca Laura, Egensperger, Rupert, Baldi, Alfonso, Dehmelt, Leif, Kaiser, Markus, Huber, Robert, Clausen, Tim, Ehrmann, Michael
Publicado em 2012

Cerebrospinal fluid–based kinetic biomarkers of axonal transport in monitoring neurodegeneration

Por Fanara, Patrizia, Wong, Po-Yin A., Husted, Kristofor H., Liu, Shanshan, Liu, Victoria M., Kohlstaedt, Lori A., Riiff, Timothy, Protasio, Joan C., Boban, Drina, Killion, Salena, Killian, Maudi, Epling, Lorrie, Sinclair, Elisabeth, Peterson, Julia, Price, Richard W., Cabin, Deborah E., Nussbaum, Robert L., Brühmann, Jörg, Brandt, Roland, Christine, Chadwick W., Aminoff, Michael J., Hellerstein, Marc K.
Publicado em 2012