Human High Temperature Requirement Serine Protease A1 (HTRA1) Degrades Tau Protein Aggregates

Protective proteases are key elements of protein quality control pathways that are up-regulated, for example, under various protein folding stresses. These proteases are employed to prevent the accumulation and aggregation of misfolded proteins that can impose severe damage to cells. The high temper...

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Main Authors: Tennstaedt, Annette, Pöpsel, Simon, Truebestein, Linda, Hauske, Patrick, Brockmann, Anke, Schmidt, Nina, Irle, Inga, Sacca, Barbara, Niemeyer, Christof M., Brandt, Roland, Ksiezak-Reding, Hanna, Tirniceriu, Anca Laura, Egensperger, Rupert, Baldi, Alfonso, Dehmelt, Leif, Kaiser, Markus, Huber, Robert, Clausen, Tim, Ehrmann, Michael
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2012
Teme:
Protein Synthesis and Degradation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375517/
https://ncbi.nlm.nih.gov/pubmed/22535953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.316232
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