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Epigenetic silencing of serine protease HTRA1 drives polyploidy
BACKGROUND: Increased numbers and improperly positioned centrosomes, aneuploidy or polyploidy, and chromosomal instability are frequently observed characteristics of cancer cells. While some aspects of these events and the checkpoint mechanisms are well studied, not all players have yet been identif...
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發表在: | BMC Cancer |
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Main Authors: | , , , , , , , , , , , , , , |
格式: | Artigo |
語言: | Inglês |
出版: |
BioMed Central
2016
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4936022/ https://ncbi.nlm.nih.gov/pubmed/27388476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2425-8 |
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