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Epigenetic silencing of serine protease HTRA1 drives polyploidy

BACKGROUND: Increased numbers and improperly positioned centrosomes, aneuploidy or polyploidy, and chromosomal instability are frequently observed characteristics of cancer cells. While some aspects of these events and the checkpoint mechanisms are well studied, not all players have yet been identif...

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書目詳細資料
發表在:BMC Cancer
Main Authors: Schmidt, Nina, Irle, Inga, Ripkens, Kamilla, Lux, Vanda, Nelles, Jasmin, Johannes, Christian, Parry, Lee, Greenow, Kirsty, Amir, Sarah, Campioni, Mara, Baldi, Alfonso, Oka, Chio, Kawaichi, Masashi, Clarke, Alan R., Ehrmann, Michael
格式: Artigo
語言:Inglês
出版: BioMed Central 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936022/
https://ncbi.nlm.nih.gov/pubmed/27388476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2425-8
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