Epigenetic silencing of serine protease HTRA1 drives polyploidy

BACKGROUND: Increased numbers and improperly positioned centrosomes, aneuploidy or polyploidy, and chromosomal instability are frequently observed characteristics of cancer cells. While some aspects of these events and the checkpoint mechanisms are well studied, not all players have yet been identif...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Schmidt, Nina, Irle, Inga, Ripkens, Kamilla, Lux, Vanda, Nelles, Jasmin, Johannes, Christian, Parry, Lee, Greenow, Kirsty, Amir, Sarah, Campioni, Mara, Baldi, Alfonso, Oka, Chio, Kawaichi, Masashi, Clarke, Alan R., Ehrmann, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936022/
https://ncbi.nlm.nih.gov/pubmed/27388476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2425-8
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