Epigenetic silencing of serine protease HTRA1 drives polyploidy

BACKGROUND: Increased numbers and improperly positioned centrosomes, aneuploidy or polyploidy, and chromosomal instability are frequently observed characteristics of cancer cells. While some aspects of these events and the checkpoint mechanisms are well studied, not all players have yet been identif...

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Bibliographic Details
Published in:BMC Cancer
Main Authors: Schmidt, Nina, Irle, Inga, Ripkens, Kamilla, Lux, Vanda, Nelles, Jasmin, Johannes, Christian, Parry, Lee, Greenow, Kirsty, Amir, Sarah, Campioni, Mara, Baldi, Alfonso, Oka, Chio, Kawaichi, Masashi, Clarke, Alan R., Ehrmann, Michael
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936022/
https://ncbi.nlm.nih.gov/pubmed/27388476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2425-8
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