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Loss of HtrA1 serine protease induces synthetic modulation of aortic vascular smooth muscle cells

Homozygous mutations of human HTRA1 cause cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL). HtrA1(-/-) mice were examined for arterial abnormalities. Although their cerebral arteries were normal, the thoracic aorta was affected in HtrA1(-/-) mice....

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ikawati, Muthi, Kawaichi, Masashi, Oka, Chio
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5955505/
https://ncbi.nlm.nih.gov/pubmed/29768431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0196628
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