Serine protease HtrA1 modulates chemotherapy-induced cytotoxicity

Resistance to chemotherapy presents a serious challenge in the successful treatment of various cancers and is mainly responsible for mortality associated with disseminated cancers. Here we show that expression of HtrA1, which is frequently downregulated in ovarian cancer, influences tumor response t...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Chien, Jeremy, Aletti, Giovanni, Baldi, Alfonso, Catalano, Vincenzo, Muretto, Pietro, Keeney, Gary L., Kalli, Kimberly R., Staub, Julie, Ehrmann, Michael, Cliby, William A., Lee, Yean Kit, Bible, Keith C., Hartmann, Lynn C., Kaufmann, Scott H., Shridhar, Viji
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2006
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1474818/
https://ncbi.nlm.nih.gov/pubmed/16767218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI27698
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