Serine protease HtrA1 modulates chemotherapy-induced cytotoxicity

Resistance to chemotherapy presents a serious challenge in the successful treatment of various cancers and is mainly responsible for mortality associated with disseminated cancers. Here we show that expression of HtrA1, which is frequently downregulated in ovarian cancer, influences tumor response t...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Chien, Jeremy, Aletti, Giovanni, Baldi, Alfonso, Catalano, Vincenzo, Muretto, Pietro, Keeney, Gary L., Kalli, Kimberly R., Staub, Julie, Ehrmann, Michael, Cliby, William A., Lee, Yean Kit, Bible, Keith C., Hartmann, Lynn C., Kaufmann, Scott H., Shridhar, Viji
التنسيق: Artigo
اللغة:Inglês
منشور في: American Society for Clinical Investigation 2006
الموضوعات:
Research Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC1474818/
https://ncbi.nlm.nih.gov/pubmed/16767218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI27698
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