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Serine protease HtrA1 modulates chemotherapy-induced cytotoxicity

Resistance to chemotherapy presents a serious challenge in the successful treatment of various cancers and is mainly responsible for mortality associated with disseminated cancers. Here we show that expression of HtrA1, which is frequently downregulated in ovarian cancer, influences tumor response t...

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Bibliografische gegevens
Hoofdauteurs: Chien, Jeremy, Aletti, Giovanni, Baldi, Alfonso, Catalano, Vincenzo, Muretto, Pietro, Keeney, Gary L., Kalli, Kimberly R., Staub, Julie, Ehrmann, Michael, Cliby, William A., Lee, Yean Kit, Bible, Keith C., Hartmann, Lynn C., Kaufmann, Scott H., Shridhar, Viji
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2006
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1474818/
https://ncbi.nlm.nih.gov/pubmed/16767218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI27698
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