Implications of the serine protease HtrA1 in amyloid precursor protein processing

The defining features of the widely conserved HtrA (high temperature requirement) family of serine proteases are the combination of a catalytic protease domain with one or more C-terminal PDZ domains and reversible zymogen activation. Even though HtrAs have previously been implicated in protein qual...

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Bibliografiske detaljer
Main Authors: Grau, Sandra, Baldi, Alfonso, Bussani, Rossana, Tian, Xiaodan, Stefanescu, Raluca, Przybylski, Michael, Richards, Peter, Jones, Simon A., Shridhar, Viji, Clausen, Tim, Ehrmann, Michael
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2005
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087941/
https://ncbi.nlm.nih.gov/pubmed/15855271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501823102
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