Imatinib spells BAD news for Bcr/abl-positive leukemias

Por Kaufmann, Scott H.
Publicado em 2006

Selectively targeting Mcl-1 for the treatment of acute myelogenous leukemia and solid tumors

Por Gores, Gregory J., Kaufmann, Scott H.
Publicado em 2012

How does doxorubicin work?

Por Patel, Anand G, Kaufmann, Scott H
Publicado em 2012

Prospects for the Use of ATR Inhibitors to Treat Cancer

Por Wagner, Jill M., Kaufmann, Scott H.
Publicado em 2010

Mitochondrial apoptosis and BH3 mimetics

Por Dai, Haiming, Meng, X. Wei, Kaufmann, Scott H.
Publicado no F1000Res (2016)

Anticancer therapy: boosting the bang of Bim

Por Hendrickson, Andrea Wahner, Meng, Xue Wei, Kaufmann, Scott H.
Publicado em 2008

Nonhomologous end joining drives poly(ADP-ribose) polymerase (PARP) inhibitor lethality in homologous recombination-deficient cells

Por Patel, Anand G., Sarkaria, Jann N., Kaufmann, Scott H.
Publicado em 2011

Poly (ADP-Ribose) Polymerase Inhibitors: Recent Advances and Future Development

Por Scott, Clare L., Swisher, Elizabeth M., Kaufmann, Scott H.
Publicado no J Clin Oncol (2015)

Evaluation of the BH3-only Protein Puma as a Direct Bak Activator

Por Dai, Haiming, Pang, Yuan-Ping, Ramirez-Alvarado, Marina, Kaufmann, Scott H.
Publicado em 2014

G(1) and G(2) cell-cycle arrest following microtubule depolymerization in human breast cancer cells

Por Blajeski, April L., Phan, Vy A., Kottke, Timothy J., Kaufmann, Scott H.
Publicado em 2002

PARP inhibition: PARP1 and beyond

Por Rouleau, Michèle, Patel, Anand, Hendzel, Michael J., Kaufmann, Scott H., Poirier, Guy G.
Publicado em 2010

The Elephant and the Blind Men: Making Sense of PARP Inhibitors in Homologous Recombination Deficient Tumor Cells

Por De Lorenzo, Silvana B., Patel, Anand G., Hurley, Rachel M., Kaufmann, Scott H.
Publicado em 2013

Context-dependent Bcl-2/Bak Interactions Regulate Lymphoid Cell Apoptosis

Por Dai, Haiming, Meng, X. Wei, Lee, Sun-Hee, Schneider, Paula A., Kaufmann, Scott H.
Publicado em 2009

Failure of Iniparib to Inhibit Poly(ADP-ribose) Polymerase in Vitro

Por Patel, Anand G., De Lorenzo, Silvana, Flatten, Karen S., Poirier, Guy G., Kaufmann, Scott H.
Publicado em 2012

The BH3 Only Protein Mimetic Obatoclax Sensitizes Cholangiocarcinoma Cells to Apo2L/TRAIL-Induced Apoptosis

Por Mott, Justin L., Bronk, Steve F., Mesa, Ruben A., Kaufmann, Scott H., Gores, Gregory J.
Publicado em 2008

Inhibition of histone deacetylase overcomes rapamycin-mediated resistance in diffuse large B-cell lymphoma by inhibiting Akt signaling through mTORC2

Por Gupta, Mamta, Ansell, Stephen M., Novak, Anne J., Kumar, Shaji, Kaufmann, Scott H., Witzig, Thomas E.
Publicado em 2009

Transient binding of an activator BH3 domain to the Bak BH3-binding groove initiates Bak oligomerization

Por Dai, Haiming, Smith, Alyson, Meng, X. Wei, Schneider, Paula A., Pang, Yuan-Ping, Kaufmann, Scott H.
Publicado em 2011

Bak Conformational Changes Induced by Ligand Binding: Insight into BH3 Domain Binding and Bak Homo-Oligomerization

Por Pang, Yuan-Ping, Dai, Haiming, Smith, Alyson, Meng, X. Wei, Schneider, Paula A., Kaufmann, Scott H.
Publicado em 2012

Contribution of Bcl-2 Phosphorylation to Bak Binding and Drug Resistance

Por Dai, Haiming, Ding, Husheng, Meng, X. Wei, Lee, Sun-Hee, Schneider, Paula A., Kaufmann, Scott H.
Publicado em 2013

Efficient method to optimize antibodies using avian leukosis virus display and eukaryotic cells

Por Yu, Changming, Pike, Gennett M., Rinkoski, Tommy A., Correia, Cristina, Kaufmann, Scott H., Federspiel, Mark J.
Publicado no Proc Natl Acad Sci U S A (2015)