Context-dependent Bcl-2/Bak Interactions Regulate Lymphoid Cell Apoptosis

The release of cytochrome c from mitochondria, which leads to activation of the intrinsic apoptotic pathway, is regulated by interactions of Bax and Bak with antiapoptotic Bcl-2 family members. The factors that regulate these interactions are, at the present time, incompletely understood. Recent stu...

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Bibliographic Details
Main Authors: Dai, Haiming, Meng, X. Wei, Lee, Sun-Hee, Schneider, Paula A., Kaufmann, Scott H.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2009
Subjects:
Mechanisms of Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709361/
https://ncbi.nlm.nih.gov/pubmed/19351886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.004770
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