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Efficient method to optimize antibodies using avian leukosis virus display and eukaryotic cells
Antibody-based therapeutics have now had success in the clinic. The affinity and specificity of the antibody for the target ligand determines the specificity of therapeutic delivery and off-target side effects. The discovery and optimization of high-affinity antibodies to important therapeutic targe...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4538638/ https://ncbi.nlm.nih.gov/pubmed/26216971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1414754112 |
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