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G(1) and G(2) cell-cycle arrest following microtubule depolymerization in human breast cancer cells
Microtubule-depolymerizing agents are widely used to synchronize cells, screen for mitotic checkpoint defects, and treat cancer. The present study evaluated the effects of these agents on normal and malignant human breast cell lines. After treatment with 1 μM nocodazole, seven of ten breast cancer l...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC151025/ https://ncbi.nlm.nih.gov/pubmed/12093892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI13275 |
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