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The kinesin-13 MCAK has an unconventional ATPase cycle adapted for microtubule depolymerization
Unlike other kinesins, members of the kinesin-13 subfamily do not move directionally along microtubules but, instead, depolymerize them. To understand how kinesins with structurally similar motor domains can have such dissimilar functions, we elucidated the ATP turnover cycle of the kinesin-13, MCAK...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3209780/ https://ncbi.nlm.nih.gov/pubmed/21873978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.290 |
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