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The kinesin-13 MCAK has an unconventional ATPase cycle adapted for microtubule depolymerization

Unlike other kinesins, members of the kinesin-13 subfamily do not move directionally along microtubules but, instead, depolymerize them. To understand how kinesins with structurally similar motor domains can have such dissimilar functions, we elucidated the ATP turnover cycle of the kinesin-13, MCAK...

詳細記述

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書誌詳細
主要な著者: Friel, Claire T, Howard, Jonathon
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209780/
https://ncbi.nlm.nih.gov/pubmed/21873978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.290
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