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A kinesin-13 mutant catalytically depolymerizes microtubules in ADP

The kinesin-13 motor protein family members drive the removal of tubulin from microtubules (MTs) to promote MT turnover. A point mutation of the kinesin-13 family member mitotic centromere-associated kinesin/Kif2C (E491A) isolates the tubulin-removal conformation of the motor, and appears distinct f...

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Detalhes bibliográficos
Main Authors: Wagenbach, Michael, Domnitz, Sarah, Wordeman, Linda, Cooper, Jeremy
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582896/
https://ncbi.nlm.nih.gov/pubmed/19001124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200805145
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